A Phase 2/3, Randomized, Double-masked, Multicenter, Dose-ranging, Sham-Controlled Clinical Trial to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
 
Link: Study Details | A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) | ClinicalTrials.gov

Randomized, Double-Masked, Active-Controlled, Phase 3 Study of the Efficacy and Safety of Aflibercept 8 mg in Patients With Macula Edema due to Retinal Vein Occlusion

Link: Study Details | A Study to Learn How Well a Higher Amount of Aflibercept Given as an Injection Into the Eye Works and How Safe it is in People With Reduced Vision Due to Swelling in the Macula, Central Part of the Retina Caused by a Blocked Vein in the Retina (Macula Edema Secondary to Retinal Vein Occlusion) | ClinicalTrials.gov

A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE MASKED, SHAM CONTROLLED STUDY TO INVESTIGATE THE EFFICACY, SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF RO7200220 ADMINISTERED INTRAVITREALLY IN PATIENTS WITH UVEITIC MACULAR EDEMA
 
Link: Study Details | Vamikibart in Participants With Uveitic Macular Edema | ClinicalTrials.gov

REAL-WORLD, LONG-TERM DATA COLLECTION TO GAIN CLINICAL INSIGHTS INTO ROCHE OPHTHALMOLOGY PRODUCT(S)

A multicenter, open-label extension study to evaluate the long-term safety and tolerability of the port delivery system with Ranibizumab in patients with neovascular age-related macular degeneration.

Link: Extension Study for the Port Delivery System With Ranibizumab (Portal) - Full Text View - ClinicalTrials.gov

Investigation of retinal pathology in Eye Diseases using High Resolution Optical Coherence Tomography (High-Res-SD-OCT)

LINK: Evaluation of Retinal Structure With High Resolution Optical Coherence Tomography (OCT) - Full Text View - ClinicalTrials.gov

A pragmatic, randomized, non-inferiority trial comparing the effectiveness of Botulinum toxin-based treatment with conventional strabismus surgery in acquired esotropia.

LINK: Botox Instead of Strabismus Surgery (BISS) - Full Text View - ClinicalTrials.gov

Development of a keratoconus detection algorithm by deep learning analysis and its validation on Eyestar images

LINK: Development of a Keratoconus Detection Algorithm by Deep Learning Analysis and Its Validation on Eyestar Images - Full Text View - ClinicalTrials.gov
 

Open label early feasibility study evaluating the safety of the SPECTRALIS CENTAURUS device for dosimetry of selective retina therapy with optical coherence tomography.

LINK: Evaluating the Safety of the SPECTRALIS CENTAURUS Device - Full Text View - ClinicalTrials.gov

2014 - ongoing The Role of the Gut Metagenome on the Development of Age Related Macular Degeneration (AMD) (Clinical trials identifier: NCT02438111) Inselspital Bern AMD

 2013 – ongoing Measurement of Retinal Auto Fluorescence With a Fluorescence Lifetime Imaging Ophthalmoscope (FLIO Group) (Clinical trials identifier: NCT01981148) Inselspital Bern

A PHASE IIIb, GLOBAL, MULTICENTER, RANDOMIZED, VISUAL ASSESSOR−MASKED STUDY OF THE EFFICACY, SAFETY, AND PHARMACOKINETICS OF A 36-WEEK REFILL REGIMEN FOR THE PORT DELIVERY SYSTEM WITH RANIBIZUMAB IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION Link

Associations of the ocular microbiome and the immune system in dry eye disease. Ocular Microbiome and Immune System in Dry Eyes - Link

A Phase 2 randomized, placebo-controlled, double-masked proof-of-concept and dose-finding study to investigate the efficacy and safety of runcaciguat (BAY 1101042) in patients with moderately severe to severe non-proliferative diabetic retinopathy Link

Correctness of diagnosing eye disease using an objective, quantitative and semi-automatic eye examination

Non-inferiority study for visual field measurements using a virtual reality device on participants with normal and glaucomatous visual fields.

Beurteilung zur Wirksamkeit und Sicherheit von Aflibercept bei einem "treat and extend" Behandlungsplan unter Anwendung eines strengen Nachbehandlungsmuster im Vergleich zu einem lockeren Nachbehandlungsmuster bei Patienten/Innen mit feuchter altersbedingter Makuladegeneration.

Informationen zu der Studie in englischer Sprache finden Sie hier:  TOLERANT

2017- ongoing Investigation of Vascular Pathology in Eye Diseases Using Optical Coherence Tomography Angiography (OCT-A) OCT-A

Selektive RPE-Lasertherapie (SRT) bei makulären Netzhauterkrankungen

Link: 

The Prevalence of patent foramen ovale in central serous chorioretinopathy (PFO in CSC)

Beurteilung zur Wirksamkeit von antiVEGF Injektionen bei einem "treat and extend" Behandlungsplan unter Anwendung eines visusgesteuerten versus optische Kohärenztomographie gesteuerten Wiederbehandlungskriterium bei Patienten/Innen mit diabetischem Makulaödem. Comparison of VA Guided Versus OCT Guided TER Using Aflibercept for Diabetic Macular Edema (AVOCT Study)AVOCT

 2018- ongoing FLIO and the Influence of Oral Lutein Supplementation on Macular Pigment

2012-ongoing. Rasageline (Azilect) – Neuroprotektion bei Makula-off Netzhautablösung Inselspital Bern

 A Multicenter, Double-Masked, Randomized,Dose-Ranging Trial to Evaluate the Efficacy and Safety of Conbercept Intravitreal Injection in Subjects with Neovascular Age-related Macular Degeneration Link